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Caliciviral protein-based artificial translational activator for mammalian gene circuits with RNA-only delivery

Hideyuki Nakanishi, Hirohide Saito

Nature Communications · 2020

doi:10.1038/s41467-020-15061-x (opens in a new tab)

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Abstract

Synthetic RNA-based circuits allow for gene regulation without the risk of mutagenesis. Here the authors demonstrate a Caliciviral VPg-based Translational activator which allows translational activation of synthetic mRNAs.

Abstract licence: CC BY-NC-ND

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