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A model of DNA damage response activation at stalled replication forks by SPRTN

Christopher Bruhn, Marco Foiani

Nature Communications · 2019

doi:10.1038/s41467-019-13610-7 (opens in a new tab)

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Abstract

The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.

Abstract licence: CC BY-NC-ND

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