Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers
Priyanka Gopal, Elif Irem Sarihan, Eui Kyu Chie and 13 more
Nature Communications · 2019
doi:10.1038/s41467-019-13161-x (opens in a new tab)
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Abstract
BRAF mutations are frequent events in many different cancer types. Here, the authors highlight how distinct BRAF mutations affect the clonal dynamics and architecture of emergent tumours, with potential implications for therapeutic intervention.
Abstract licence: CC BY-NC-ND
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