Differential regulation of OCT4 targets facilitates reacquisition of pluripotency
Sudhir Thakurela, Camille Sindhu, Evgeny Yurkovsky and 4 more
Nature Communications · 2019
doi:10.1038/s41467-019-11741-5 (opens in a new tab)
We email you when a new notice or a question about this paper appears.
Abstract
Barriers underlying the inefficiency of reprogramming cells to pluripotency are poorly defined. Here the authors identify a transient interval soon after pluripotency exit that permits high-efficiency reprogramming and is facilitated by OCT4 bound elements displaying unique silencing behaviour during differentiation.
Abstract licence: CC BY-NC-ND
Reads
Read by people on this page
None yet.
Checked or read by AI through naulon
None yet.
A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.
Are you an author?
Is this your paper?
Claim it to add your note and be paid when agents cite it. Free.