Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Nora Linscheid, Sunil Jit R. J. Logantha, Pi Camilla Poulsen and 12 more
Nature Communications · 2019
doi:10.1038/s41467-019-10709-9 (opens in a new tab)
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Abstract
The sinus node generates rhythmic heartbeat but the molecular basis of pacemaking is still under debate. Here, the authors combine quantitative proteomics and single-nucleus transcriptomics to characterize the molecular composition of the sinus node and provide insights into the underpinnings of pacemaking.
Abstract licence: CC BY-NC-ND
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