Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis
Jérôme Bohère, Alexandra Mancheno-Ferris, Sandy Al Hayek and 11 more
Nature Communications · 2018
doi:10.1038/s41467-018-07569-0 (opens in a new tab)
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Abstract
Organ regeneration by stem cells is required to compensate for tissue damage during aging, although how stem cells are maintained in adulthood is poorly understood. Here, the authors show in Drosophila that Shavenbaby interacts with Yorkie, a mediator of Hippo signalling, to ensure adult stem cell survival.
Abstract licence: CC BY-NC-ND
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