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Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci

Christopher G. Bell, Fei Gao, Wei Yuan and 9 more

Nature Communications · 2018

doi:10.1038/s41467-017-01586-1 (opens in a new tab)

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Abstract

Genomic polymorphisms affect the epigenome, which in turn influences how epigenome- and genome-wide analysis are interpreted. Here, the authors characterise allelic differences in DNA methylation driven by obligatory or facilitative genetic effects, which may affect disease-related loci.

Abstract licence: CC BY-NC-ND

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