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Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate

Wei Dai, Amy Peterson, Thomas Kenney and 2 more

Nature Communications · 2017

doi:10.1038/s41467-017-01322-9 (opens in a new tab)

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Abstract

In the Drosophila ovary, it is unclear how signalling from the stem cell niche regulates follicle precursor cell fate/differentiation. Here, the authors use quantitative microscopy to define the role of Wnt, Hedgehog and Notch signalling in progenitor cells, showing regulation of cell fate and differentiation.

Abstract licence: CC BY-NC-ND

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