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Genome-wide prediction of DNase I hypersensitivity using gene expression

Weiqiang Zhou, Ben Sherwood, Zhicheng Ji and 5 more

Nature Communications · 2017

doi:10.1038/s41467-017-01188-x (opens in a new tab)

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Abstract

A map of the activities of all genomic regulatory elements across cell types and conditions would be a tremendous resource. The computational method introduced here predicts genome-wide accessible sites from gene expression data and allows the authors to build a database of regulatory element activities using publicly available transcriptome data.

Abstract licence: CC BY-NC-ND

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