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Reproductive fitness and genetic risk of psychiatric disorders in the general population

Niamh Mullins, Andrés Ingason, Heather Porter and 15 more

Nature Communications · 2017

doi:10.1038/ncomms15833 (opens in a new tab)

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Abstract

Why genetic variants that confer risk for psychiatric disorders persist in the genome is an evolutionary conundrum. Here, Mullinset al. report association of polygenic risk for autism with having fewer children and polygenic risk for ADHD with higher reproductive fitness.

Abstract licence: CC BY-NC-ND

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