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Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin

Ruifang Guan, Lei Zhang, Qian Peter Su and 6 more

Nature Communications · 2017

doi:10.1038/ncomms14951 (opens in a new tab)

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Abstract

Kinesins are molecular motors that travel along microtubules through a nucleotide-dependent stepping mechanism. Here the authors present the crystal structure of Zen4 (kinesin-6) in an apo state that sheds light on a key stepping intermediate of kinesin.

Abstract licence: CC BY-NC-ND

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