Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
S. Dallari, M. Macal, M. E. Loureiro and 5 more
Nature Communications · 2017
doi:10.1038/ncomms14830 (opens in a new tab)
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Abstract
Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.
Abstract licence: CC BY-NC-ND
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