Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA
Evgenij Fiskin, Sagar Bhogaraju, Lina Herhaus and 3 more
Nature Communications · 2017
doi:10.1038/ncomms14004 (opens in a new tab)
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Abstract
The HECT-like E3 ligase SopA inSalmonellahas been suggested to activate host RING ligases TRIM56 and TRIM65. Here, the authors use mass spectrometry, crystal structures and biochemistry to examine the interactions between these proteins in detail.
Abstract licence: CC BY-NC-ND
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