17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
Benjamin Joachim Schmiedel, Grégory Seumois, Daniela Samaniego-Castruita and 7 more
Nature Communications · 2016
doi:10.1038/ncomms13426 (opens in a new tab)
We email you when a new notice or a question about this paper appears.
Abstract
Variations in the 17q21 locus are linked to asthma susceptibility and other autoimmune diseases. Here, the authors perform cell type-specific functional genomic analyses of asthma-risk SNPs, and show a genotype specific mechanism of differential gene regulation relevant to immune function.
Abstract licence: CC BY-NC-ND
Reads
Read by people on this page
None yet.
Checked or read by AI through naulon
None yet.
A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.
Are you an author?
Is this your paper?
Claim it to add your note and be paid when agents cite it. Free.