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Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging

Feng Tian, Wenlong Yang, Daniel A. Mordes and 18 more

Nature Communications · 2016

doi:10.1038/ncomms13283 (opens in a new tab)

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Abstract

Sensitive and label-free imaging methods to visualize nerve degeneration are currently lacking. Here authors show that stimulated Raman scattering (SRS) microscopy can be used to monitor peripheral nerve degeneration in mouse models of amyotrophic lateral sclerosis (ALS) and in postmortem tissue from ALS patients.

Abstract licence: CC BY-NC-ND

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