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A time transect of exomes from a Native American population before and after European contact

John Lindo, Emilia Huerta-Sánchez, Shigeki Nakagome and 7 more

Nature Communications · 2016

doi:10.1038/ncomms13175 (opens in a new tab)

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Abstract

A First Nation population declined after European contact, likely as a result of infectious disease. Here, researchers partner with indigenous communities to analyse ancient and modern Native American exomes, and find a shift in selection pressure on immune genes, correlated to European-borne epidemics.

Abstract licence: CC BY-NC-ND

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