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Antagonistic roles of Drosophila Tctp and Brahma in chromatin remodelling and stabilizing repeated sequences

Sung-Tae Hong, Kwang-Wook Choi

Nature Communications · 2016

doi:10.1038/ncomms12988 (opens in a new tab)

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Abstract

Genome stability is important for normal cellular function. Here, Hong and Choi show that translationally controlled tumour protein (TCTP) in Drosophilaregulates pericentromeric chromatin remodelling and transcription via negatively regulating a chromatin remodeler Brahma.

Abstract licence: CC BY-NC-ND

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