Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity
Naoto Kubota, Tetsuya Kubota, Eiji Kajiwara and 15 more
Nature Communications · 2016
doi:10.1038/ncomms12977 (opens in a new tab)
We email you when a new notice or a question about this paper appears.
Abstract
Type 2 diabetes and obesity are associated with increased hepatic gluconeogenesis and lipogenesis, known as selective insulin resistance. Here Kubota et al. explain selective insulin resistance in the liver with the zonal distribution and selective insulin-mediated regulation of Irs1 and Irs2.
Abstract licence: CC BY-NC-ND
Cited by papers we hold3
Reads
Read by people on this page
None yet.
Checked or read by AI through naulon
None yet.
A person counts once a day per paper. We keep no cookie and no address: a reader is a hash that changes every day. Any month under five reads shows no number.
Are you an author?
Is this your paper?
Claim it to add your note and be paid when agents cite it. Free.