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Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing

Parisa Kakanj, Bernard Moussian, Sebastian Grönke and 4 more

Nature Communications · 2016

doi:10.1038/ncomms12972 (opens in a new tab)

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Abstract

The TOR and insulin/IGF signalling (IIS) network are central responses to wound healing. Here the authors develop a technique of live imaging of laser-induced epidermal wounds to flies and show that TOR and IIS are independently required for wound healing, which may have implications for diabetic wound healing and its treatment.

Abstract licence: CC BY-NC-ND

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