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Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination

Ryan J. Bourgo, Hari Singhal, Geoffrey L. Greene

Nature Communications · 2016

doi:10.1038/ncomms12893 (opens in a new tab)

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Abstract

Chromatin architecture is a key regulator of transcriptional processes, however current methods to investigate it have technical limitations. Here, the authors describe a novel chromatin capture technique, CATCH, which can be used to identify and characterize complex genomic interaction networks.

Abstract licence: CC BY-NC-ND

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