The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation
Mehrpouya B. Mobin, Stefanie Gerstberger, Daniel Teupser and 6 more
Nature Communications · 2016
doi:10.1038/ncomms12848 (opens in a new tab)
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Abstract
RNA-binding proteins (RBP) are an emerging group of post-translational regulators. Here the authors show that the RBP vigilin regulates translation of mRNA encoding for proatherogenic proteins—apoB, apoC-III and fibronectin—representing a potential therapeutic target in cardiovascular diseases.
Abstract licence: CC BY-NC-ND
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