Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
Mathew Stracy, Marcin Jaciuk, Stephan Uphoff and 4 more
Nature Communications · 2016
doi:10.1038/ncomms12568 (opens in a new tab)
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Abstract
Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.
Abstract licence: CC BY-NC-ND
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