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RNA editing generates cellular subsets with diverse sequence within populations

Dewi Harjanto, Theodore Papamarkou, Chris J. Oates and 3 more

Nature Communications · 2016

doi:10.1038/ncomms12145 (opens in a new tab)

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Abstract

RNA editing rate detected from bulk RNA-seq data can vary widely. Here, by constructing a hierarchical Bayesian model, the authors report substantial variance in editing signatures detected by RNA-seq data from both single cells and a cognate bulk sample.

Abstract licence: CC BY-NC-ND

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