Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus
Ruijun Zhang, David R. Martinez, Quang N. Nguyen and 18 more
Nature Communications · 2016
doi:10.1038/ncomms12131 (opens in a new tab)
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Abstract
Infection of African green monkeys with simian immunodeficiency virus is a potential model for HIV vaccine development. Here, Zhang et al. catalogue the immunoglobulin loci present in the genome of these animals, and experimentally study their B-cell response to the viral envelope protein.
Abstract licence: CC BY-NC-ND
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