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RNA polymerase I–Rrn3 complex at 4.8 Å resolution

Christoph Engel, Jürgen Plitzko, Patrick Cramer

Nature Communications · 2016

doi:10.1038/ncomms12129 (opens in a new tab)

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Abstract

RNA polymerase I is the central enzyme that synthesizes ribosomal RNA in eukaryotic cells, and its regulation underlies cell growth. Here the authors present a high-resolution cryo-EM structure of the Pol I-Rrn3 complex that explains how Rrn3 specifically recognizes Pol I to form an initiation competent complex.

Abstract licence: CC BY-NC-ND

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