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Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes

Rachel Barrow-McGee, Naoki Kishi, Carine Joffre and 14 more

Nature Communications · 2016

doi:10.1038/ncomms11942 (opens in a new tab)

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Abstract

Cooperative signalling between receptor tyrosine kinases (RTKs) and integrins is thought to occur at the cell surface. Here the authors show that β1 integrin influences signalling of an RTK, c-Met, from a novel intracellular compartment they call autophagy-related endomembranes.

Abstract licence: CC BY-NC-ND

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