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Common genetic variation in ETV6 is associated with colorectal cancer susceptibility

Meilin Wang, Dongying Gu, Mulong Du and 21 more

Nature Communications · 2016

doi:10.1038/ncomms11478 (opens in a new tab)

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Abstract

Genome-wide association studies have been performed to identify genetic variants that are associated with susceptibility to colorectal cancer. Here, the authors expand on these studies and identify a variant that regulates the expression of ETV6 and find that over-expression of ETV6 blocks cell proliferation in vitro.

Abstract licence: CC BY-NC-ND

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