Common genetic variation in ETV6 is associated with colorectal cancer susceptibility
Meilin Wang, Dongying Gu, Mulong Du and 21 more
Nature Communications · 2016
doi:10.1038/ncomms11478 (opens in a new tab)
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Abstract
Genome-wide association studies have been performed to identify genetic variants that are associated with susceptibility to colorectal cancer. Here, the authors expand on these studies and identify a variant that regulates the expression of ETV6 and find that over-expression of ETV6 blocks cell proliferation in vitro.
Abstract licence: CC BY-NC-ND
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