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Aurora A drives early signalling and vesicle dynamics during T-cell activation

Noelia Blas-Rus, Eugenio Bustos-Morán, Ignacio Pérez de Castro and 9 more

Nature Communications · 2016

doi:10.1038/ncomms11389 (opens in a new tab)

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Abstract

Aurora A is a protein kinase that contributes to the progression of mitosis by stimulating microtubule nucleation. Here the authors show that Aurora A also functions during T cell activation by maintaining TCR signaling through Lck activation.

Abstract licence: CC BY-NC-ND

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