Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability
Makoto Iimori, Sugiko Watanabe, Shinichi Kiyonari and 6 more
Nature Communications · 2016
doi:10.1038/ncomms11117 (opens in a new tab)
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Abstract
Temporal regulation of microtubule dynamics in mitosis can be achieved by phosphorylation of microtubule plus-end proteins. Here, the authors show that Aurora B and CDK1 phosphorylate EB2, which changes microtubule binding affinity and controls kinetochore microtubule dynamics and genome stability.
Abstract licence: CC BY-NC-ND
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