Regulation of cell-to-cell variability in divergent gene expression
Chao Yan, Shuyang Wu, Christopher Pocetti and 1 more
Nature Communications · 2016
doi:10.1038/ncomms11099 (opens in a new tab)
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Abstract
Gene expression noise affects cell fitness and development. Here, Yan et al. show that co-regulated divergent gene pairs (DGPs) suppress uncorrelated gene expression noise due to more synchronized transcription firing, and differentially regulated DGPs enhance gene expression noise due to transcription leakage.
Abstract licence: CC BY-NC-ND
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