Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
Lorena Mendive-Tapia, Can Zhao, Ahsan R. Akram and 8 more
Nature Communications · 2016
doi:10.1038/ncomms10940 (opens in a new tab)
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Abstract
Functionalizing antimicrobial peptides with fluorescent groups is a useful strategy for imaging infection, but the tag can alter the performance of the probe. Here, the authors report a spacer-free method to directly functionalise an amino acid with a fluorogenic group and prepare peptide-based imaging agents for fungal infection.
Abstract licence: CC BY-NC-ND
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