E2F function in muscle growth is necessary and sufficient for viability in Drosophila
Maria Paula Zappia, Maxim V. Frolov
Nature Communications · 2016
doi:10.1038/ncomms10509 (opens in a new tab)
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Abstract
The transcriptional regulators E2F/Dp play a critical role in cell-cycle regulation, but it is unclear why E2F-deficient flies die. Here, the authors show this is linked to the function of E2F in adult Drosophilaskeletal muscle, with the contribution of E2f1 being most important in post-fusion muscle.
Abstract licence: CC BY-NC-ND
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