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TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage

Nam Soo Lee, Hee Jin Chung, Hyoung-June Kim and 11 more

Nature Communications · 2016

doi:10.1038/ncomms10463 (opens in a new tab)

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Abstract

Recruiting DNA damage repair factors to the sites of DNA damage is critical for the maintenance of genome integrity. Here the authors identify that the TRAF-interacting protein (TRAIP/RNF206) is required for normal recruitment of RAP80 to DNA lesions and the stimulation of homologous recombination.

Abstract licence: CC BY-NC-ND

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