Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus
Raehee Park, Uk Yeol Moon, Jun Young Park and 4 more
Nature Communications · 2016
doi:10.1038/ncomms10329 (opens in a new tab)
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Abstract
Failure of the ependymal cell layer that lines the ventricular surfaces of the brain can result in fetal hydrocephalus. Park et al. reveal a role for the Hippo pathway gene Yap in the generation of ependymal cells, and show that suppression of Yap is observed in a model of hydrocephalus.
Abstract licence: CC BY-NC-ND
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