Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing
Benjamin L. Oakes, Danny F. Xia, Elizabeth F. Rowland and 8 more
Nature Communications · 2016
doi:10.1038/ncomms10194 (opens in a new tab)
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Abstract
Zinc finger nucleases have an established role in genome editing. Here, the authors report a strategy for identifying zinc finger nucleases that discriminate between desired targets and provide genome-wide specificity.
Abstract licence: CC BY-NC-ND
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