The IciStem consortium: T-cell immunology in HIV-1 infected individuals after allogeneic stem cell transplantation
J. Eberhard, M. Angin, C. Passaes and 7 more
Journal of Virus Eradication · 2019
doi:10.1016/s2055-6640(20)30156-4 (opens in a new tab)
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Abstract
Conclusions: We efficiently combined index single cell sorting of p24-expressing cells with near full-length HIV genome sequencing to characterize individual infected cells from ART-treated individuals.Our analysis reveals the diversity in the phenotype of cells harboring identical proviral sequence and suggests that clonal expansions of HIV genomes contributes to the diversification of the pool of HIV reservoir cells.
Abstract licence: CC BY-NC-ND
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