Commentary: Changing the equation by boosting the numeratorCentral Message

Despite all the recent advances in organ-procurement organizations, allocation system, increased use of extended-criteria donors, use of lungs from donation after cardiac death donors, and increase in number of centers performing lung transplants globally, the number of patients requiring lung transplant each year continues to grow. Even though the number of donors continues to steadily increase, in the United States fewer than 1 in 4 pairs of lungs offered for donation will be eventually used for transplant, and hundreds of thousands of people around the world continue to die each year from end-stage lung disease.

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