Opinion: miRNAs – The new wave of molecular cancer therapeutics
Hernando Lopez-Bertoni, John Laterra
Translational Oncology · 2021
doi:10.1016/j.tranon.2021.101064 (opens in a new tab)
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Abstract
Cutting-edge advances in nanomedicine and the recent approval of two siRNA-based therapeutics by the Food and Drug Administration (FDA) has rekindled the interest in RNA interference (RNAi) as vehicles for the development of novel cancer therapeutics. In this perspective, we will briefly discuss how miRNAs are becoming the next-generation RNAi therapeutic, the advances in delivery vehicles for in vivo miRNA delivery, and where miRNA technology stands in terms of clinical translation.
Abstract licence: CC BY-NC
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