Lung transplantation following donation after circulatory death

• Lung transplantation, a potentially life-saving therapy, remains significantly limited due to donor organ availability. • Donation after circulatory death (DCD) is a promising clinical endeavor that may increase the donor pool for viable organs with successful post-transplant outcomes. • The clinical setting and circumstances surrounding DCD are important in successful recovery. • Controlled DCD lung transplantation has success rates similar to lung transplantation following donation after brain death (DBD). • The evolving application of extracorporeal circulation technology, both the ex vivo lung perfusion (EVLP) modality as well as the more recent thoracoabdominal normothermic regional perfusion (TA-NRP), could have a leading role in the optimization of DCD transplants soon.

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