Mitochondrial Functions in Infection and Immunity

Abstract

Mitochondria have a central role in regulating a range of cellular activities and host responses upon bacterial infection. Multiple pathogens affect mitochondria dynamics and functions to influence their intracellular survival or evade host immunity. On the other side, major host responses elicited against infections are directly dependent on mitochondrial functions, thus placing mitochondria centrally in maintaining homeostasis upon infection. In this review, we summarize how different bacteria and viruses impact morphological and functional changes in host mitochondria and how this manipulation can influence microbial pathogenesis as well as the host cell metabolism and immune responses.

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Cited by papers we hold 6

• The Key Role of Mitochondrial Function in Health and Disease · 2023
  No notice
• Acinetobacter baumannii Secretes a Bioactive Lipid That Triggers Inflammatory Signaling and Cell Death · 2022
  Not checked
• Unraveling the Mystery Surrounding Post-Acute Sequelae of COVID-19 · 2021
  No notice
• Impact of COVID-19 on Mitochondrial-Based Immunity in Aging and Age-Related Diseases · 2021
  Not checked
• Mitochondrial function in development and disease · 2021
  No notice
• Mitochondria: In the Cross Fire of SARS-CoV-2 and Immunity · 2020
  Not checked

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