SLAS special issue editorial 2022: 3D cell culture approaches of microphysiologically relevant models

Not long ago, researchers were skeptical of the value of culturing cells in a 3D environment. Today, 3D cell culture has become a routine tool that plays a vital role in drug discovery and life sciences research. 3D cell culture approaches are still relatively new despite their early impact, and there is still ambiguity in the robustness of culturing techniques, the readiness of supply chain, and even the use of nomenclature depicting 3D morphology. The value of 3D cell cultures is defined by the increased dimensionality and access to contact between cells to generate a phenotype predictive of in vivo biology but performed in vitro.

Abstract licence: CC BY-NC-ND

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