Editorial: Preprocedural Computational Modeling — One More Step Toward Precision Medicine in Transcatheter Aortic Valve Replacement?
Ole De Backer, MD, PhD, Maarten Vanhaverbeke, MD, PhD
Structural Heart · 2022
doi:10.1016/j.shj.2022.100045 (opens in a new tab)
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Abstract
In a decade’s time, transcatheter aortic valve replacement (TAVR) has evolved from a treatment option reserved for patients with severe, symptomatic aortic stenosis (AS) with a high surgical risk profile to a standard and preferred treatment option for nearly all severe AS patients ≥75 years regardless of the degree of surgical risk.1 In this same period, technological improvements in transcatheter heart valve (THV) systems have led to a significant increase in efficacy and safety of TAVR. Newer-generation devices with external sealing skirts have addressed the issue of paravalvular regurgitation (PVR), and delivery systems with a smaller insertion profile allow for a safe transfemoral approach.
Abstract licence: CC BY-NC-ND
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