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Progress of esophageal stricture prevention after endoscopic submucosal dissection by regenerative medicine and tissue engineering

Xian-bin Zhou, Shi-wen Xu, Li-ping Ye and 7 more

Regenerative Therapy · 2021

doi:10.1016/j.reth.2021.01.003 (opens in a new tab)

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Abstract

Endoscopic submucosal dissection (ESD) has been widely accepted as an effective treatment for early esophageal cancer. However, post-ESD esophageal stricture remains a thorny issue. We herein review many strategies for preventing post-ESD esophageal stricture, as well as discuss their strengths and weaknesses. These strategies include pharmacological prophylaxis, esophageal stent and tissue engineering and regenerative medicine treatment. In this review, we summarize these studies and discuss the underlying progress and future directions of tissue engineering and regenerative medicine treatment.

Abstract licence: CC BY-NC-ND

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