Giant cell tumor of a rib following denosumab treatment
Alexandre Semionov, John Kosiuk
Radiology Case Reports · 2018
doi:10.1016/j.radcr.2018.04.005 (opens in a new tab)
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Abstract
Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on computed tomography imaging following treatment with denosumab. Keywords: Giant cell tumor, Denosumab, Osteosclerosis
Abstract licence: CC BY-NC-ND
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