Kinase activity is required for the toxic effects of mutant LRRK2/dardarin

Cited by papers we hold 23

• Perspective on the current state of the LRRK2 field · 2023
  No notice
• The effect of LRRK2 loss-of-function variants in humans · 2020
  Corrected
• Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease · 2020
  No notice
• LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients · 2019
  No notice
• PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins · 2019
  No notice
• LRRK2 modifies α-syn pathology and spread in mouse models and human neurons · 2019
  No notice
• The interplay of aging, genetics and environmental factors in the pathogenesis of Parkinson’s disease · 2019
  No notice
• Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase · 2018
  No notice
• Rab29 activation of the Parkinson's disease‐associated LRRK2 kinase · 2017
  Corrected
• Back to the tubule: microtubule dynamics in Parkinson’s disease · 2016
  No notice
• Cellular processes associated with LRRK 2 function and dysfunction · 2015
  No notice
• Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations · 2014
  No notice
• A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation · 2014
  No notice
• Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily · 2013
  No notice
• Inhibition of LRRK2 kinase activity stimulates macroautophagy · 2013
  No notice
• LRRK2: Cause, Risk, and Mechanism · 2013
  No notice
• GTPase Activity and Neuronal Toxicity of Parkinson's Disease–Associated LRRK2 Is Regulated by ArfGAP1 · 2012
  No notice
• Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2 · 2011
  No notice
• Phosphorylation-Dependent 14-3-3 Binding to LRRK2 Is Impaired by Common Mutations of Familial Parkinson's Disease · 2011
  Corrected
• GTPase Activity Plays a Key Role in the Pathobiology of LRRK2 · 2010
  No notice

and 3 more

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