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First bloodstream infection due to Prototheca zopfii var. hydrocarbonea in an immunocompromised patient

Norma B. Fernández, Constanza G. Taverna, Matías Vivot and 2 more

Medical Mycology Case Reports · 2019

doi:10.1016/j.mmcr.2019.02.003 (opens in a new tab)

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Abstract

Here we describe a bloodstream infection due to P. zopfii var. hydrocarbonea in a patient with acute lymphoblastic leukemia. Identification was performed by DNA sequencing of the D1/D2 domain of 26s ribosomal DNA and by MALDI-TOF MS technique. Antifungal susceptibility tests against amphotericin B, fluconazole, itraconazole, and voriconazole showed the following MIC values, respectively: 0.25 mg/L, 128 mg/L, 0.064 mg/L, and 0.125 mg/L. The patient received amphotericin B treatment with a successful outcome. Keywords: Prototheca spp, Protothecosis, P.zopfii, Bloodstream infection, Immunocompromised patient

Abstract licence: CC BY-NC-ND

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