The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
Philip D. Bright, Duncan Lupiya, Joep J. van Oosterhout and 3 more
Medical Mycology Case Reports · 2018
doi:10.1016/j.mmcr.2017.10.002 (opens in a new tab)
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Abstract
This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed to the development of cryptococcal disease. The patient was successfully treated with two weeks of amphotericin B followed by fluconazole, delivered a healthy baby, but remained with a permanent severe neurological deficit.
Abstract licence: CC BY-NC-ND
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