Cutaneous squamous cell carcinoma arising within a mycosis fungoides patch: Case report and review of the literature
Elnara Muradova, MD, Nupur Patel, MD, Pei-Ling Chen, MD and 1 more
JAAD Case Reports · 2020
doi:10.1016/j.jdcr.2020.09.016 (opens in a new tab)
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Abstract
Mycosis fungoides (MF) is the most common type of primary cutaneous T-cell lymphoma (CTCL) and is defined as clonal proliferation of skin-infiltrating atypical T lymphocytes. Patients with MF have increased risk for both primary hematologic malignancies and secondary solid tumors.1 However, the development of squamous cell carcinoma (SCC) in skin that is affected by MF is extremely rare. The majority of previously reported cases of SCC in patients with MF have been described following treatment with skin-directed therapies, including topical nitrogen mustard, total skin electron beam radiation, psoralen and ultraviolet A treatment, and narrow-band ultraviolet B therapy.
Abstract licence: CC BY
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