Lenalidomide-Induced Myocarditis, Rare But Possibly Fatal Toxicity of a Commonly Used Immunotherapy
Robin Jacob, MD, Paolo Strati, MD, Nicolas Palaskas, MD and 5 more
JACC: Case Reports · 2020
doi:10.1016/j.jaccas.2020.07.033 (opens in a new tab)
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Abstract
A 66-year-old woman with follicular lymphoma on lenalidomide and rituximab presented with chest pain. High-sensitivity troponin T peaked at 7,566 ng/l. Cardiac biopsy revealed extensive inflammation consistent with medication-induced myocarditis. Lenalidomide was stopped with improvement in troponins and patient was initiated on high-dose corticosteroid therapy. (Level of Difficulty: Intermediate.)
Abstract licence: CC BY-NC-ND
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