2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families

Abstract

This international multidisciplinary document intends to provide clinicians with evidence-based practical patient-centered recommendations for evaluating patients and decedents with (aborted) sudden cardiac arrest and their families. The document includes a framework for the investigation of the family allowing steps to be taken, should an inherited condition be found, to minimize further events in affected relatives. Integral to the process is counseling of the patients and families, not only because of the emotionally charged subject, but because finding (or not finding) the cause of the arrest may influence management of family members. The formation of multidisciplinary teams is essential to provide a complete service to the patients and their families, and the varied expertise of the writing committee was formulated to reflect this need. The document sections were divided up and drafted by the writing committee members according to their expertise. The recommendations represent the consensus opinion of the entire writing committee, graded by Class of Recommendation and Level of Evidence. The recommendations were opened for public comment and reviewed by the relevant scientific and clinical document committees of the Asia Pacific Heart Rhythm Society (APHRS) and the Heart Rhythm Society (HRS); the document underwent external review and endorsement by the partner and collaborating societies. While the recommendations are for optimal care, it is recognized that not all resources will be available to all clinicians. Nevertheless, this document articulates the evaluation that the clinician should aspire to provide for patients with sudden cardiac arrest, decedents with sudden unexplained death, and their families.

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References 362

1. 1.

   Halperin JL, Levine GN, Al-Khatib SM, Further evolution of the ACC/AHA clinical practice guideline recommendation classification system: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol 2016;67:1572–1574.

   Not in our library10.1016/j.jacc.2015.09.001

2. 2.

   Fellmann F, van El CG, Charron P, European recommendations integrating genetic testing into multidisciplinary management of sudden cardiac death. Eur J Hum Genet 2019;27:1763–1773.

   Not in our library10.1038/s41431-019-0445-y

3. 3.
   2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias · 2020

   No notice
4. 4.

   Towbin JA, McKenna WJ, Abrams DJ, 2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy. Heart Rhythm 2019;16:e301–e372.

   Not in our library10.1016/j.hrthm.2019.05.007

5. 5.

   Brignole M, Moya A, de Lange FJ, 2018 ESC guidelines for the diagnosis and management of syncope. Eur Heart J 2018;39:1883–1948.

   Not in our library10.1093/eurheartj/ehy037

6. 6.

   Al-Khatib SM, Stevenson WG, Ackerman MJ, 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Heart Rhythm 2018;15:e73–e189.

   Not in our library10.1016/j.hrthm.2017.10.036

7. 7.

   Mont L, Pelliccia A, Sharma S, Pre-participation cardiovascular evaluation for athletic participants to prevent sudden death: position paper from the EHRA and the EACPR, branches of the ESC. Europace 2017;19:139–163.

   Not in our library10.1093/europace/euw243

8. 8.

   Priori SG, Blomstrom-Lundqvist C, Mazzanti A, 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J 2015;36:2793–2867.

   Not in our library10.1093/eurheartj/ehv445

9. 9.

   Pedersen CT, Kay GN, Kalman J, EHRA/HRS/APHRS expert consensus on ventricular arrhythmias. Heart Rhythm 2014;11:e166–e196.

   Not in our library10.1016/j.hrthm.2014.07.024

10. 10.

    Priori SG, Wilde AA, Horie M, HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes. Heart Rhythm 2013;10:1932–1963.

    Not in our library10.1016/j.hrthm.2013.05.014

11. 11.

    Ackerman MJ, Priori SG, Willems S, HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies. Heart Rhythm 2011;8:1308–1339.

    Not in our library10.1016/j.hrthm.2011.05.020

12. 12.

    Zipes DP, Camm AJ, Borggrefe M, ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (writing committee to develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death). Circulation 2006;114:e385–e484.

    Not in our library10.1161/circulationaha.106.178233

13. 13.

    Fishman GI, Chugh SS, Dimarco JP, Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop. Circulation 2010;122:2335–2348.

    Not in our library10.1161/circulationaha.110.976092

14. 14.

    Risgaard B, Lynge TH, Wissenberg M, Risk factors and causes of sudden noncardiac death: a nationwide cohort study in Denmark. Heart Rhythm 2015; 12:968–974.

    Not in our library10.1016/j.hrthm.2015.01.024

15. 15.

    Winkel BG, Holst AG, Theilade J, Nationwide study of sudden cardiac death in persons aged 1–35 years. Eur Heart J 2011;32:983–990.

    Not in our library10.1093/eurheartj/ehq428

16. 16.

    Sanchez O, Campuzano O, Fernandez-Falgueras A, Natural and undetermined sudden death: value of post-mortem genetic investigation. PLoS One 2016;11:e0167358.

    Not in our library10.1371/journal.pone.0167358

17. 17.

    Nichol G, Thomas E, Callaway CW, Regional variation in out-of-hospital cardiac arrest incidence and outcome. JAMA 2008;300:1423–1431.

    Not in our library10.1001/jama.300.12.1423

18. 18.

    Chugh SS, Jui J, Gunson K, Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large U.S. community. J Am Coll Cardiol 2004;44:1268–1275.

    Not in our library10.1016/j.jacc.2004.06.029

19. 19.

    de Vreede-Swagemakers JJ, Gorgels AP, Dubois-Arbouw WI, Out-of-hospital cardiac arrest in the 1990’s: a population-based study in the Maastricht area on incidence, characteristics and survival. J Am Coll Cardiol 1997; 30:1500–1505.

    Not in our library10.1016/s0735-1097(97)00355-0

20. 20.

    Stecker EC, Reinier K, Marijon E, Public health burden of sudden cardiac death in the United States. Circ Arrhythm Electrophysiol 2014;7:212–217.

    Not in our library10.1161/circep.113.001034

21. 21.

    Wong CX, Brown A, Lau DH, Epidemiology of sudden cardiac death: global and regional perspectives. Heart Lung Circ 2019;28:6–14.

    Not in our library10.1016/j.hlc.2018.08.026

22. 22.

    Kong MH, Fonarow GC, Peterson ED, Systematic review of the incidence of sudden cardiac death in the United States. J Am Coll Cardiol 2011;57:794–801.

    Not in our library10.1016/j.jacc.2010.09.064

23. 23.

    Kitamura T, Iwami T, Kawamura T, Nationwide improvements in survival from out-of-hospital cardiac arrest in Japan. Circulation 2012;126:2834–2843.

    Not in our library10.1161/circulationaha.112.109496

24. 24.

    Gillum RF. Sudden coronary death in the United States: 1980–1985. Circulation 1989;79:756–765.

    Not in our library10.1161/01.cir.79.4.756

25. 25.

    Bagnall RD, Weintraub RG, Ingles J, A prospective study of sudden cardiac death among children and young adults. N Engl J Med 2016;374:2441–2452.

    Not in our library10.1056/nejmoa1510687

26. 26.

    Wisten A, Krantz P, Stattin EL. Sudden cardiac death among the young in Sweden from 2000 to 2010: an autopsy-based study. Europace 2017;19:1327–1334.

    Not in our library10.1093/europace/euw249

27. 27.

    Risgaard B, Winkel BG, Jabbari R, Burden of sudden cardiac death in persons aged 1 to 49 years: nationwide study in Denmark. Circ Arrhythm Electrophysiol 2014;7:205–211.

    Not in our library10.1161/circep.113.001421

28. 28.

    Byrne R, Constant O, Smyth Y, Multiple source surveillance incidence and aetiology of out-of-hospital sudden cardiac death in a rural population in the West of Ireland. Eur Heart J 2008;29:1418–1423.

    Not in our library10.1093/eurheartj/ehn155

29. 29.

    Winkel BG, Risgaard B, Sadjadieh G, Bundgaard H, Haunso S, Tfelt-Hansen J. Sudden cardiac death in children (1–18 years): symptoms and causes of death in a nationwide setting. Eur Heart J 2014;35:868–875.

    Not in our library10.1093/eurheartj/eht509

30. 30.

    Burns KM, Cottengim C, Dykstra H, Epidemiology of sudden death in a population-based study of infants and children. J Pediatr: X 2020;2:100023.

    Not in our library10.1016/j.ympdx.2020.100023

31. 31.

    Eckart RE, Shry EA, Burke AP, Sudden death in young adults: an autopsy-based series of a population undergoing active surveillance. J Am Coll Cardiol 2011;58:1254–1261.

    Not in our library10.1016/j.jacc.2011.01.049

32. 32.

    Thiene G, Corrado D, Basso C. The Northeast Italy, Veneto Region experience. In: Thiene G, Corrado D, Basso C, eds. Sudden Cardiac Death in the Young and Athletes. Springer-Verlag Milan; 2016. p. 171–181.

    Not in our library

33. 33.

    Chappex N, Schlaepfer J, Fellmann F, Bhuiyan ZA, Wilhelm M, Michaud K. Sudden cardiac death among general population and sport related population in forensic experience. J Forensic Leg Med 2015;35:62–68.

    Not in our library10.1016/j.jflm.2015.07.004

34. 34.

    Deo R, Albert CM. Epidemiology and genetics of sudden cardiac death. Circulation 2012;125:620–637.

    Not in our library10.1161/circulationaha.111.023838

35. 35.

    Becker LB, Han BH, Meyer PM, Racial differences in the incidence of cardiac arrest and subsequent survival: the CPR Chicago Project. N Engl J Med 1993;329:600–606.

    Not in our library10.1056/nejm199308263290902

36. 36.

    Zhao D, Post WS, Blasco-Colmenares E, Racial differences in sudden cardiac death. Circulation 2019;139:1688–1697.

    Not in our library10.1161/circulationaha.118.036553

37. 37.

    Behr ER, Casey A, Sheppard M, Sudden arrhythmic death syndrome: a national survey of sudden unexplained cardiac death. Heart 2007;93:601–605.

    Not in our library10.1136/hrt.2006.099598

38. 38.

    Griffis H, Wu L, Naim MY, Characteristics and outcomes of AED use in pediatric cardiac arrest in public settings: the influence of neighborhood characteristics. Resuscitation 2020;146:126–131.

    Not in our library10.1016/j.resuscitation.2019.09.038

39. 39.

    Starks MA, Schmicker RH, Peterson ED, Association of neighborhood demographics with out-of-hospital cardiac arrest treatment and outcomes: where you live may matter. JAMA Cardiol 2017;2:1110–1118.

    Not in our library10.1001/jamacardio.2017.2671

40. 40.

    Basso C, Calabrese F, Corrado D, Thiene G. Postmortem diagnosis in sudden cardiac death victims: macroscopic, microscopic and molecular findings. Cardiovasc Res 2001;50:290–300.

    Not in our library10.1016/s0008-6363(01)00261-9

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